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These limitations highlight the necessity for carefully designed future trials targeting appropriate disease stages and patient populations
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CV cardiovascular, CVD cardiovascular disease, CVOT cardiovascular outcome trial, GLP-1 glucagon-like peptide 1, HR hazard ratio, MACE major cardiovascular events, SC subcutaneous, T2DM type 2 diabetes mellitus, Vs versus a Not currently available on the market Anti-atherogenic mechanisms of semaglutide Studies to elucidate the cardiovascular protection mechanisms of GLP-1 have been conducted over the years, but they are not completely understood
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